Noninvasive Technique for Monitoring Chorioretinal Temperature during Transpupillary Thermotherapy, with a Thermosensitive Liposome
نویسندگان
چکیده
منابع مشابه
Noninvasive technique for monitoring chorioretinal temperature during transpupillary thermotherapy, with a thermosensitive liposome.
PURPOSE To develop a technique for noninvasive and real-time monitoring of chorioretinal temperature in transpupillary thermotherapy (TTT). METHOD A modified slit lamp, which was equipped with two laser wavelengths (490 nm for illumination and fluorescein excitation and 810 nm for hyperthermia), was developed for TTT and temperature monitoring. Five types of liposomes were prepared, and their...
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PURPOSE To assess a biological effect induced by temperature elevation during transpupillary thermotherapy (TTT). METHODS Six pigmented rabbits were anesthetized, and TTT was performed on the right eye using an 810-nm diode laser installed on a slit lamp (spot size, 1.3 mm; duration, 60 seconds; power, 92-150 mW). A series of laser pulses were aimed at the posterior pole of the retina. The le...
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grad u ally changed in re cent years from enucle ation or ex ter nal beam ra di a tion ther apy to fo cal con ser va tive meth ods. Thermotherapy is one of the new est meth ods in this re gard. When cou pled with che mo ther apy, it pro vides sat is fac tory con trol in se lected cases. The pres ent case was a child with his left eye enucleated pre vi ously for ret i no blas toma. The multifoca...
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BACKGROUND Central serous chorioretinopathy (CSC) has been traditionally treated with laser photocoagulation. We thought that transpupillary thermotherapy (TTT) utilizing a lower temperature than that of conventional laser photocoagulation might minimize permanent retinal and choroidal damage. Studies suggest that undesirable effects on vision due to TTT are minimal even if it is applied to fov...
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Laser-induced thermotherapy (LITT) is a hyperthermic procedure recently employed to treat cancer in several organs. The amount of coagulated tissue depends on the temperature distribution around the applicator, which plays a crucial role for an optimal outcome: the removal of the whole neoplastic tissue, whilst preventing damage to the surrounding healthy tissue. Although feedback concerning ti...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2003
ISSN: 1552-5783
DOI: 10.1167/iovs.02-1210